Flora 717 is a sanitation worker in a highly regimented dictatorship that happens to be a beehive. Through a combination of luck and unusual talents in one of her origins, she able to transcend her place and learn many roles in the hive from serving in the nursery to foraging. But when she accidentally commits a grave crime, and the hive is in trouble, she finds herself doing things she would previously have thought unthinkable.
I have to say, I think that the comparisons to The Handmaid's Tale, The Hunger Games, and even Animal Farm are out of place. Our Flora actually does appear to be biologically different from the rest of the floras; we're told more than once that it's unusual that she's capable of "speech." And I won't go into the later events of the book. Therefore I'd say that comparisons to human dystopias are off because in the case of books about repressive human societies, we are talking about people who are created equal, for lack of a better phrase, when it's clear that Flora 717 is something "better" than the rest of the floras. And even in Animal Farm, the point is that the pigs take over a society in which all creatures with four legs are supposed to be equal, and not that most of the non-pigs really are inferior and the exceptions are special.
That said, the anthropomorphic look at a beehive in trouble through the eyes of a worker is an inventive idea and wonderfully handled (particularly keeping in mind that Flora 717 does not have a human scientist's external perspective of hive function). Just look at it as an exercise in worldbuilding, don't push the symbolism too far, and enjoy the ride.
Overall: A